Inspired by the characters of Lot Pot Comics, Motu Patlu is a lively comic caper for the kids as well as the entire family. Set in the beautiful city of Furfuri Nagariya, the story is about Motu and Patlu, who are as similar as chalk and cheese. The Awesome Twosome are always on an adventurous expedition and have an uncanny ability to get into tricky situations every single day! It was premiered on 16 October 2012, beginning with the episode "John Banega Don". It focuses on two friends, Motu and Patlu, living in the fictional city Furfuri Nagar.

Motu and Patlu are best friends. When trouble engulfs the village, they team up to save the day.

Tiger Chang, a martial arts master from a village located in the Himalayas, visits Furfuri Nagar. After defeating the boxers in a boxing competition, he insults the people of Furfuri Nagar. To restore the prestige of Furfuri Nagar, Motu decides to learn martial arts and defeat Tiger Chang. Can Motu overcome Tiger Chang's challenge and restore the pride of Furfuri Nagar? Watch to find out!

Motu-Patlu, Dr. Jhatka, Ghaseetaram and Inspector Chingum are on a road trip to Switzerland. Meanwhile, A Polar bear promises his cubs that he will give them a special cake for their birthday. He starts searching when he comes across Motu. Will Motu fall for this trap?

Loosely based on Victor Hugo's Les Miserables.